From 37f584592ad7ac1ce9644b14bf96a2620be0b237 Mon Sep 17 00:00:00 2001
From: Mădălin Ionel Patrașcu <madalinionel.patrascu@mdc-berlin.de>
Date: Wed, 27 Apr 2022 13:44:36 +0200
Subject: gnu: Add r-aggregatebiovar.

* gnu/packages/bioconductor.scm (r-aggregatebiovar): New variable.

Signed-off-by: Ricardo Wurmus <rekado@elephly.net>
---
 gnu/packages/bioconductor.scm | 34 ++++++++++++++++++++++++++++++++++
 1 file changed, 34 insertions(+)

diff --git a/gnu/packages/bioconductor.scm b/gnu/packages/bioconductor.scm
index 3d68db6d68..b760db2db7 100644
--- a/gnu/packages/bioconductor.scm
+++ b/gnu/packages/bioconductor.scm
@@ -1821,6 +1821,40 @@ and meta analysis at both gene and gene-set levels of the data from each
 experiment.")
     (license license:gpl2+)))
 
+(define-public r-aggregatebiovar
+  (package
+    (name "r-aggregatebiovar")
+    (version "1.4.0")
+    (source (origin
+              (method url-fetch)
+              (uri (bioconductor-uri "aggregateBioVar" version))
+              (sha256
+               (base32
+                "1wbfp1pf62di6pzxsf36lmzk6y9dllz1n4iv3mhpb1x8cvy4hqqk"))))
+    (properties `((upstream-name . "aggregateBioVar")))
+    (build-system r-build-system)
+    (propagated-inputs
+     (list r-matrix
+           r-rlang
+           r-s4vectors
+           r-singlecellexperiment
+           r-summarizedexperiment
+           r-tibble))
+    (native-inputs (list r-knitr))
+    (home-page "https://github.com/jasonratcliff/aggregateBioVar")
+    (synopsis "Differential gene expression analysis for multi-subject scRNA-seq")
+    (description
+     "This package @code{aggregateBioVar} contains tools to summarize single
+cell gene expression profiles at the level of subject for single cell RNA-seq
+data collected from more than one subject (e.g. biological sample or technical
+replicates).  A @code{SingleCellExperiment} object is taken as input and
+converted to a list of @code{SummarizedExperiment} objects, where each list
+element corresponds to an assigned cell type.  The @code{SummarizedExperiment}
+objects contain aggregate gene-by-subject count matrices and inter-subject
+column metadata for individual subjects that can be processed using downstream
+bulk RNA-seq tools.")
+    (license license:gpl3)))
+
 (define-public r-aneufinder
   (package
     (name "r-aneufinder")
-- 
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